EccDNA formation is dependent on MMEJ, repressed by c-NHEJ pathway, and stimulated by DNA double-strand break
Selected by
Sree Rama Chaitanya
ALC1 links chromatin accessibility to PARP inhibitor response in homologous recombination deficient cells
Selected by
Giuseppina D'Alessandro
Evolution of mouse circadian enhancers from transposable elements
Selected by
Miguel V. Almeida
The hourglass model of evolutionary conservation during embryogenesis extends to developmental enhancers with signatures of positive selection
Selected by
Irepan Salvador-Martinez
CENP-A chromatin prevents replication stress at centromeres to avoid structural aneuploidy
Selected by
Sree Rama Chaitanya
ARID1A regulates R-loop associated DNA replication stress
Selected by
Sree Rama Chaitanya
Poly-ADP-ribosylation drives loss of protein homeostasis in ATM and Mre11 deficiency
Selected by
Sree Rama Chaitanya
SF3B1-targeted Splicing Inhibition Triggers Global Alterations in Transcriptional Dynamics and R-Loop Metabolism
Selected by
Sree Rama Chaitanya
Live-cell imaging shows uneven segregation of extrachromosomal DNA elements and transcriptionally active extrachromosomal DNA clusters in cancer
Selected by
Sree Rama Chaitanya
High-throughput discovery and characterization of human transcriptional effectors
Selected by
Clarice Hong
Severe immunodeficiency in mice lacking DNA repair factors XLF and Mri
Selected by
Jennifer Ann Black
SUMO orchestrates multiple alternative DNA-protein crosslink repair pathways
Selected by
Vanessa Kellner